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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Ekologiya cheloveka (Human Ecology)</journal-id><journal-title-group><journal-title xml:lang="en">Ekologiya cheloveka (Human Ecology)</journal-title><trans-title-group xml:lang="ru"><trans-title>Экология человека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1728-0869</issn><issn publication-format="electronic">2949-1444</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">16689</article-id><article-id pub-id-type="doi">10.33396/1728-0869-2018-5-28-32</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">CHRONOPHYSIOLOGICAL FEATURES OF THE NORMAL ELECTROLYTE COMPOSITION OF HUMAN SALIVA</article-title><trans-title-group xml:lang="ru"><trans-title>Хронофизиологические особенности электролитного состава слюны человека в норме</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bel'skaya</surname><given-names>L V</given-names></name><name xml:lang="ru"><surname>Бельская</surname><given-names>Людмила Владимировна</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат химических наук, доцент кафедры химической технологии и биотехнологии; директор по науке</p></bio><email>LudaB2005@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sarf</surname><given-names>E A</given-names></name><name xml:lang="ru"><surname>Сарф</surname><given-names>Е А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kosenok</surname><given-names>V K</given-names></name><name xml:lang="ru"><surname>Косенок</surname><given-names>В К</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Massard</surname><given-names>Zh</given-names></name><name xml:lang="ru"><surname>Массард</surname><given-names>Ж</given-names></name></name-alternatives><xref ref-type="aff" rid="aff4"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Omsk State Technical University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Омский государственный технический университет»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">ChemService</institution></aff><aff><institution xml:lang="ru">ООО «ХимСервис»</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Omsk State Medical University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Омский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">University Hospital of Strasbourg</institution></aff><aff><institution xml:lang="ru">Университетская больница Страсбурга</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-05-15" publication-format="electronic"><day>15</day><month>05</month><year>2018</year></pub-date><volume>25</volume><issue>5</issue><issue-title xml:lang="en">NO5 (2018)</issue-title><issue-title xml:lang="ru">№5 (2018)</issue-title><fpage>28</fpage><lpage>32</lpage><history><date date-type="received" iso-8601-date="2019-10-23"><day>23</day><month>10</month><year>2019</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2018, Human Ecology</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2018, Экология человека</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="en">Human Ecology</copyright-holder><copyright-holder xml:lang="ru">Экология человека</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://hum-ecol.ru/1728-0869/article/view/16689">https://hum-ecol.ru/1728-0869/article/view/16689</self-uri><abstract xml:lang="en"><p>A high rate of change in the composition of saliva can be used to monitor biorhythms (seasonal and circadian). Research objective -the study of the dynamics of the near-24-hour mineral composition of saliva in men and women. Methods. The study involved 40 people (20 men, 20 women, age 23.1 ± 0.9 years). Saliva samples were collected every 3 hours during the day. The mineral composition of saliva was defined by the capillary electrophoresis technique. The cross-group differences were evaluated using the non-parametric criterion. Results. It is shown that the sodium concentration reaches its maximum values at night (9.67 mM), and then monotonously decreases to 12-15 p.m. (5.72 mM). For potassium concentration, the maximum is observed around 12 p.m. (10.71 mM), remains at a stably high level until 21 p.m., after which it decreases until 6:00 a.m. in the morning (8.78 mM). For the Na/K ratio, one maximum is observed, corresponding to 3 a.m. in the night (Na/K = 1.257), and one minimum at 12-13 p.m. (Na/K = 0.666; р = 0.0082). Conclusion. Thus, the diurnal dynamics of the parameters studied is characterized by pronounced periodicity. The revealed regularities are caused by a change in the rate of saliva secretion during the day, and by the action of hormones.</p></abstract><trans-abstract xml:lang="ru"><p>Высокую скорость изменения состава слюны можно использовать для мониторинга биоритмов (сезонных, циркадианных). Цель работы - изучение околосуточной динамики электролитного состава слюны у мужчин и женщин. Методы. В исследовании приняли участие 40 человек - 20 мужчин, 20 женщин в возрасте (23,1 ± 0,9) года. Пробы слюны собирали в течение суток каждые 3 часа. Электролитный состав слюны определен методом капиллярного электрофореза. Межгрупповые различия оценены непараметрическим критерием. Результаты. Показано, что концентрация натрия достигает максимальных значений в ночные часы (9,67 ммоль/л), а затем монотонно убывает до 12-15 часов дня (5,72 ммоль/л). Для концентрации калия максимум наблюдается в районе 12 часов дня (10,71 ммоль/л), сохраняется на стабильно высоком уровне до 21 часа вечера, после чего снижается вплоть до 6 часов утра (8,78 ммоль/л). Для коэффициента Na/K наблюдается один максимум, соответствующий 3 часам ночи (Na/K = 1,257), и минимум в 12-13 часов дня (Na/K = 0,666; р = 0,0082). Вывод. Околосуточная динамика исследуемых параметров характеризуется ярко выраженной периодичностью. Выявленные закономерности обусловлены изменением скорости секреции слюны в течение суток, а также действием гормонов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>saliva</kwd><kwd>chronophysiology</kwd><kwd>electrolyte composition</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>слюна</kwd><kwd>хронофизиология</kwd><kwd>электролитный состав</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Геворкян Э. С., Минасян С. М., Абраамян Э. Т. 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