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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Ekologiya cheloveka (Human Ecology)</journal-id><journal-title-group><journal-title xml:lang="en">Ekologiya cheloveka (Human Ecology)</journal-title><trans-title-group xml:lang="ru"><trans-title>Экология человека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1728-0869</issn><issn publication-format="electronic">2949-1444</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">633894</article-id><article-id pub-id-type="doi">10.17816/humeco633894</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL STUDY ARTICLES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Preferred fruit and vegetable consumption and colonic microbiota in young residents of Arkhangelsk</article-title><trans-title-group xml:lang="ru"><trans-title>Потребление предпочитаемых овощей и фруктов и микробиота толстой кишки у молодых жителей Архангельска</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>年轻阿尔汉格尔斯克居民偏好蔬菜水果的摄入与结肠微生物群的关系</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3371-1485</contrib-id><contrib-id contrib-id-type="spin">1844-4439</contrib-id><name-alternatives><name xml:lang="en"><surname>Kukalevskaya</surname><given-names>Natalia N.</given-names></name><name xml:lang="ru"><surname>Кукалевская</surname><given-names>Наталья Николаевна</given-names></name><name xml:lang="zh"><surname>Kukalevskaya</surname><given-names>Natalia N.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>n.kukalevskaya@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7890-2341</contrib-id><contrib-id contrib-id-type="spin">2220-2151</contrib-id><name-alternatives><name xml:lang="en"><surname>Bazhukova</surname><given-names>Tatyana A.</given-names></name><name xml:lang="ru"><surname>Бажукова</surname><given-names>Татьяна Александровна</given-names></name><name xml:lang="zh"><surname>Bazhukova</surname><given-names>Tatyana A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Sci (Med), Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><email>tbazhukova@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5642-3019</contrib-id><contrib-id contrib-id-type="spin">8585-3051</contrib-id><name-alternatives><name xml:lang="en"><surname>Sabanaev</surname><given-names>Michael A.</given-names></name><name xml:lang="ru"><surname>Сабанаев</surname><given-names>Михаил Алексеевич</given-names></name><name xml:lang="zh"><surname>Sabanaev</surname><given-names>Michael A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>mix.sabanaeff@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5464-0498</contrib-id><contrib-id contrib-id-type="spin">5118-0081</contrib-id><name-alternatives><name xml:lang="en"><surname>Grjibovski</surname><given-names>Andrej M.</given-names></name><name xml:lang="ru"><surname>Гржибовский</surname><given-names>Андрей Мечиславович</given-names></name><name xml:lang="zh"><surname>Grjibovski</surname><given-names>Andrej M.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, MPhil, PhD</p></bio><bio xml:lang="ru"><p>PhD</p></bio><email>a.grjibovski@yandex.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Northern State Medical University</institution></aff><aff><institution xml:lang="ru">Северный государственный медицинский университет</institution></aff><aff><institution xml:lang="zh">Northern State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Northern (Arctic) Federal University n.a. M.V. Lomonosov</institution></aff><aff><institution xml:lang="ru">Северный (Арктический) федеральный университет им. М.В. Ломоносова</institution></aff><aff><institution xml:lang="zh">Northern (Arctic) Federal University n.a. M.V. Lomonosov</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">M.K. Ammosov North-Eastern Federal University</institution></aff><aff><institution xml:lang="ru">Северо-Восточный федеральный университет им. М.К. Аммосова</institution></aff><aff><institution xml:lang="zh">M.K. Ammosov North-Eastern Federal University</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2024-11-06" publication-format="electronic"><day>06</day><month>11</month><year>2024</year></pub-date><pub-date date-type="pub" iso-8601-date="2024-12-12" publication-format="electronic"><day>12</day><month>12</month><year>2024</year></pub-date><volume>31</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>279</fpage><lpage>290</lpage><history><date date-type="received" iso-8601-date="2024-06-27"><day>27</day><month>06</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-10-07"><day>07</day><month>10</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Эко-Вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2024, Eco-Vector</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><copyright-holder xml:lang="zh">Eco-Vector</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://hum-ecol.ru/1728-0869/article/view/633894">https://hum-ecol.ru/1728-0869/article/view/633894</self-uri><abstract xml:lang="en"><p><bold>Background: </bold>The composition of colonic microbiota is influenced by environmental factors, including dietary habits. Several studies on dietary habits and nutrition of Arctic residents have been published, but the information on the associations between fruit and vegetable consumption and gut microbiota is scarce.</p> <p><bold>Aim: </bold>This study aimed to evaluate the impact of preferred fruit and vegetable consumption on colonic microbiota in young residents of Arkhangelsk, using a sample of students and staff from a medical university.</p> <p><bold>Material and methods: </bold>The study included 90 healthy volunteers (23 men and 67 women) from Northern State Medical University in Arkhangelsk aged 18–45 years with a normal body mass index. Fruit and vegetable consumption was assessed using a questionnaire. Stool samples were collected for molecular genetic analysis of colonic microbiota. Associations between fruit and vegetable consumption and concentrations of 33 microbiota indicators were examined using multivariable median regression, with adjustments made for age, gender, and place of origin.</p> <p><bold>Results: </bold>Vegetables and fruits were consumed daily by 43.33% and 15.56% of respondents, respectively. The most frequently consumed vegetables were tomatoes (77.78%) and cucumbers (80.0%), while only 25.00% consumed potatoes and carrots. Among fruits, apples were consumed most frequently (74.44%), followed by bananas (57.78%) and citrus fruits (41.11%). Significant associations were found between Methanobrevibacter smithii and tomatoes ( p =0.008) and carrots ( p =0.006), between Prevotella spp. and cucumbers ( p =0.032), Blautia spp. and carrots ( p =0.002) and bananas ( p =0.020). Additionally, association was found for Acinetobacter spp. with tomatoes ( p =0.036), potatoes ( p =0.028) and citrus fruits ( p =0.019), Bifidobacterium spp. with potatoes ( p =0.039) and citrus fruits ( p =0.002). Direct association was found between Bacteroides spp. and cucumbers ( p =0.023).</p> <p><bold>Conclusion: </bold>Our findings on the associations between selected fruits and vegetables and microbial concentrations may contribute to the development of personalized and balanced diet to enrich microbiota biodiversity and improve the quality of life of the residents of the North.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование. </bold>Состав микробиоты подвержен воздействиям окружающей среды, в том числе пищевого поведения. Имеется достаточное количество исследований по изучению характера и особенностей питания у жителей Севера, однако информации о влиянии овощей и фруктов на микробиоту северян крайне мало.</p> <p><bold>Цель. </bold>Изучить влияние потребления предпочитаемых овощей и фруктов на микробиоту толстой кишки у молодых жителей Архангельска на примере студентов и сотрудников медицинского вуза.</p> <p><bold>Материал и методы. </bold>В исследовании приняли участие 90 человек (23 мужчины и 67 женщин) из числа сотрудников и студентов СГМУ. Критерии включения: возраст от 18 до 45 лет, практически здоровые лица, индекс массы тела в пределах нормы, без острых и хронических воспалительных заболеваний на момент исследования. Употребление овощей и фруктов оценивали по данным анкетирования. Материалом для молекулярно-генетического исследования представителей микробиоты толстой кишки являлись фекалии. Оценку связи между употреблением овощей и фруктов и микробиотой проводили с помощью многомерных медианных регрессионных моделей с коррекцией на пол, возраст и регион постоянного проживания для каждого из 33 показателей микробиоты.</p> <p><bold>Результаты. </bold>Ежедневно овощи употребляли 43,33% респондентов, фрукты — 15,56%. Чаще всего участники потребляли томаты (77,78%) и огурцы (80,00%), лишь 25,00% употребляли картофель и морковь. Среди фруктов чаще всего потребляли яблоки (74,44%), далее бананы (57,78%) и цитрусовые (41,11%). Значимые связи обнаружены между <italic>Methanobrevibacter smithii </italic>и томатами ( <italic>р </italic>=0,008), а также морковью ( <italic>р </italic>=0,006), между <italic>Prevotella </italic>spp <italic>. </italic>и огурцами ( <italic>р </italic>=0,032), между <italic>Blautia </italic>spp. и морковью ( <italic>р </italic>=0,002), бананами ( <italic>р </italic>=0,020). Концентрация <italic>Acinetobacter </italic>spp. была связана с томатами ( <italic>р </italic>=0,036), картофелем ( <italic>р </italic>=0,028) и цитрусовыми ( <italic>р </italic>=0,019), а <italic>Bifidobacterium </italic>spp. — с картофелем ( <italic>р </italic>=0,039) и цитрусовыми ( <italic>р </italic>=0,002). Прямая связь выявлена между <italic>Bacteroides </italic>spp и огурцами ( <italic>р </italic>=0,023).</p> <p><bold>Заключение. </bold>Выявлены значимые связи между употреблением ряда овощей и фруктов и численностью отдельных микроорганизмов. Знания об алиментарных факторах, влияющих на микробиоту, позволяют составлять персонифицированный и сбалансированный рацион для обогащения биоразнообразия микробиоты и улучшения качества жизни северян.</p></trans-abstract><trans-abstract xml:lang="zh"><p>背景 。 微生物群的组成受多种环境因素的影响，其中饮食行为是关键因素之一。尽管北方居民饮食特点的研究已有较多文献支持，但有关蔬菜和水果摄入对北方居民微生物群影响的研究仍极其有限。</p> <p>研究目的。 分析阿尔汉格尔斯克年轻居民（以医科大学的学生和工作人员为例）对蔬菜和水果的偏好及其与结肠微生物群组成之间的关系。</p> <p>材料与方法。 研究纳入90名参与者（23名男性和67名女性），均为北方国立医科大学的学生或工作人员。入选标准包括：18至45岁之间、身体健康、体重指数正常，以及在研究期间无急性或慢性炎症性疾病。通过问卷调查评估蔬菜和水果的摄入情况，并通过粪便样本进行结肠微生物群的分子遗传学分析。利用多变量中位数回归模型评估33种微生物群指标与蔬菜和水果摄入的关系，调整因素包括性别、年龄和常住地区。</p> <p>结果。 每日食用蔬菜的参与者占43.33%，每日食用水果的参与者占15.56%。最常食用的蔬菜是番茄（77.78%）和黄瓜（80.00%），土豆和胡萝卜的摄入率相对较低（25.00%）。最常见的水果包括苹果（74.44%）、香蕉（57.78%）和柑橘类水果（41.11%）。显著关联如下：Methanobrevibacter smithii 与番茄（ p =0.008）和胡萝卜（ p =0.006）显著相关；Prevotella spp. 与黄瓜（ p =0.032）显著相关；Blautia spp. 与胡萝卜（ p =0.002）和香蕉（ p =0.020）显著相关；Acinetobacter spp. 与番茄（p=0.036）、土豆（ p =0.028）和柑橘类水果（ p =0.019）显著相关；Bifidobacterium spp. 与土豆（ p =0.039）和柑橘类水果（ p =0.002）显著相关； Bacteroides spp. 与黄瓜（ p =0.023）显著相关。</p> <p>结论。 研究表明，特定蔬菜和水果的摄入显著影响某些微生物的数量和分布。更深入地研究饮食因素对微生物群的影响，有助于为北方居民制定个性化饮食方案，从而改善微生物群的多样性与整体生活质量。</p></trans-abstract><kwd-group xml:lang="en"><kwd>microbiota</kwd><kwd>colon</kwd><kwd>vegetables</kwd><kwd>fruits</kwd><kwd>Arctic</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>микробиота</kwd><kwd>толстая кишка</kwd><kwd>овощи</kwd><kwd>фрукты</kwd><kwd>Арктика</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>微生物群</kwd><kwd>结肠</kwd><kwd>蔬菜</kwd><kwd>水果</kwd><kwd>北极地区</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Yudina YuV, Korsunsky AA, Aminova AI, et al. 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