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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Ekologiya cheloveka (Human Ecology)</journal-id><journal-title-group><journal-title xml:lang="en">Ekologiya cheloveka (Human Ecology)</journal-title><trans-title-group xml:lang="ru"><trans-title>Экология человека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1728-0869</issn><issn publication-format="electronic">2949-1444</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">645370</article-id><article-id pub-id-type="doi">10.17816/humeco645370</article-id><article-id pub-id-type="edn">VGFKOV</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL STUDY ARTICLES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The relation between heart rate variability and the atherogenicity coefficient in northern men</article-title><trans-title-group xml:lang="ru"><trans-title>Показатели вариабельности сердечного ритма у мужчин-северян в зависимости от коэффициента атерогенности</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>北方男性心率变异性指标取决于动脉粥样硬化系数</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4511-6782</contrib-id><contrib-id contrib-id-type="spin">9402-0363</contrib-id><name-alternatives><name xml:lang="en"><surname>Averyanova</surname><given-names>Inessa V.</given-names></name><name xml:lang="ru"><surname>Аверьянова</surname><given-names>Инесса Владиславовна</given-names></name><name xml:lang="zh"><surname>Averyanova</surname><given-names>Inessa V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Sci. (Biology), Professor FEB RAS</p></bio><bio xml:lang="ru"><p>д-р биол. наук, профессор ДВО РАН</p></bio><bio xml:lang="zh"><p>Dr. Sci. (Biology), Professor FEB RAS</p></bio><email>Inessa1382@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Scientific Research Center “Arktika” Far Eastern Branch of the Russian Academy of Sciences</institution></aff><aff><institution xml:lang="ru">Научно-исследовательский центр «Арктика» Дальневосточного отделения Российской академии наук</institution></aff><aff><institution xml:lang="zh">Scientific Research Center “Arktika” Far Eastern Branch of the Russian Academy of Sciences</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-03-16" publication-format="electronic"><day>16</day><month>03</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-04-08" publication-format="electronic"><day>08</day><month>04</month><year>2025</year></pub-date><volume>31</volume><issue>9</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>647</fpage><lpage>656</lpage><history><date date-type="received" iso-8601-date="2025-01-10"><day>10</day><month>01</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-02-13"><day>13</day><month>02</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Эко-Вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2025,</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://hum-ecol.ru/1728-0869/article/view/645370">https://hum-ecol.ru/1728-0869/article/view/645370</self-uri><abstract xml:lang="en"><p><bold>Background:<italic> </italic></bold>The autonomic nervous control of the cardiovascular system can be altered in individuals with dyslipidemia and lipid metabolism disorders.</p> <p><bold>Aim:</bold> This study aimed to comparatively analyse short-term cardio interval recordings in a sample of Northern men and to simultaneously assess main values of the lipid pictures according to the atherogenicity coefficient.</p> <p><bold>Materials and methods:</bold> One hundred and eighteen men aged 28–58 (mean age was 42.5±0.5 yrs) participated in the survey which was performed with photometric, immunochemiluminescent research methods, as well as standard methods for assessing heart rate variability and physical development.</p> <p><bold>Results:</bold> The data obtained in our study showed that 53% of the surveyed men exhibited atherogenic disorders in lipid metabolism, while 47% of subjective lipid pictures showed perfect values. We found significant differences in 17 of 22 indicators of physical development, biochemical profile, and heart rate variability. That suggested the increasing relative activity of the parasympathetic link of autonomic nervous regulation observed in subjects with perfect values of lipid metabolism while those with high values of the atherogenicity coefficient demonstrated autonomic imbalance which could be seen in relatively high sympathetic activity along with the reduced influence of parasympathetic activity in the autonomic control of the circulatory system with simultaneous association with overweight and accelerated proportion of the total body fat.</p> <p><bold>Conclusion:</bold> The impaired lipid profile proved to be closely related to the dominance of sympathetic activity that is assumed to be an unfavorable predictor of the risk for cardiovascular complications. In general, the results are intended to spread the use of the heart rate variability assessing method since it shows both autonomic and physiological aspects related, particularly, to the lipid profile and somatometric status, which undoubtedly emphasizes the potential of these indicators to obtain markers for the circulatory system proper functioning.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование.</bold> Вегетативный нервный контроль сердечно-сосудистой системы может быть изменён у лиц с дислипидемией и нарушениями липидного обмена.</p> <p><bold>Цель.</bold> Сравнительный анализ кратковременных записей кардиоинтервалограмм в выборке мужчин-северян с одновременной оценкой основных характеристик липидограмм в зависимости от величины коэффициента атерогенности.</p> <p><bold>Материалы и методы. </bold>В исследованиях приняли участие 118 мужчин 28–58 лет (средний возраст 42,5±0,5 года). Использовали фотометрические, иммунохемилюминесцентные методы исследования, а также стандартные методы оценки вариабельности сердечного ритма и физического развития.</p> <p><bold>Результаты.</bold> Полученные данные показали, что у 53% обследованных мужчин имелись атерогенные нарушения липидного обмена, тогда как для 47% были характерны оптимальные показатели липидограмм. Установлено, что из 22 анализируемых показателей физического развития, биохимического профиля, а также вариабельности сердечного ритма значимые различия отмечены по 17 показателям. Результаты позволяют сделать заключение об увеличении относительной активности парасимпатического звена вегетативной нервной регуляции в выборке мужчин с оптимальными показателями липидного обмена. Для группы лиц с высокими величинами коэффициента атерогенности характерно наличие вегетативного дисбаланса, проявляющегося относительно высокой симпатической активностью на фоне снижения влияния парасимпатической активности в вегетативном контроле системы кровообращения с одновременной ассоциацией с избыточной массой тела и возрастанием доли общего содержания жира в организме.</p> <p><bold>Заключение.</bold> Полученные результаты позволили установить, что лица с нарушением липидного профиля характеризуются относительным доминированием симпатической активности, что предполагает достаточно неблагоприятное прогностическое значение в качестве предиктора риска осложнения сердечно-сосудистых заболеваний. В целом результаты настоящего исследования направлены на расширение использования метода оценки вариабельности сердечного ритма, отражающего как вегетативные, так и физиологические аспекты, связанные в том числе с липидным профилем и соматометрическим статусом, что подчёркивает потенциал совокупности данных показателей для получения перспективных маркеров благополучия системы кровообращения.</p></trans-abstract><trans-abstract xml:lang="zh"><p>论证。血脂异常和脂质代谢紊乱患者的心血管系统自主神经控制可能会发生改变。</p> <p>目的。根据动脉粥样硬化系数的数值，比较分析样本中北方男性心血管间歇图的短期记录，同时评估血脂图的主要特征。</p> <p>材料和方法。在研究中，118名28～58岁的男性（平均年龄为42.5±0.5岁）参与了研究。使用了光度学、荧光免疫化学检测方法，还采用了标准的心率变异性和身体发育评估方法。</p> <p>结果。所获得的数据显示，53%的受检男性存在动脉粥样硬化的脂质代谢紊乱，而47%的受检男性具有最佳的脂类谱分析指标。已确认，在22项分析的身体发展指标、生物化学概况，以及心律变异性中，有17项指标显示出显著差异。根据这些结果可以得出结论，在具有最佳脂质代谢指标的男性样本中，自律神经调节的副交感神经环节的相对活动有所增加。动脉粥样硬化系数高的人群的特点是自律神经失衡，表现为交感神经活动相对较高，而副交感神经活动对循环系统自律神经控制的影响却在下降，同时，还伴有体重过重和体内总脂肪比例增加。</p> <p>结论。研究结果表明，血脂异常人群的交感神经活动相对占优势，这表明交感神经活动作为心血管疾病并发症风险的预测因子，具有相当不利的预后意义。总体而言，本研究的结果旨在扩大心率变异性评估方法的使用范围，该方法同时反映了与血脂状况和体格测量状况等相关的自律神经和生理方面，为了获得循环系统良好的远景指示标，强调这些指标的整体潜力。</p></trans-abstract><kwd-group xml:lang="en"><kwd>men</kwd><kwd>Northeast of Russia</kwd><kwd>lipid spectrum</kwd><kwd>heart rate variability</kwd><kwd>dyslipidemia</kwd><kwd>atherogenicity</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>мужчины</kwd><kwd>северо-восток России</kwd><kwd>липидный спектр</kwd><kwd>вариабельность сердечного ритма</kwd><kwd>дислипидемия</kwd><kwd>атерогенность</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>男性</kwd><kwd>俄罗斯东北部</kwd><kwd>血脂谱</kwd><kwd>心率变异性</kwd><kwd>血脂异常</kwd><kwd>动脉粥样硬化</kwd></kwd-group><funding-group><award-group><funding-source><institution-wrap><institution xml:lang="ru">Министерство науки и высшего образования Российской Федерации</institution></institution-wrap><institution-wrap><institution xml:lang="en">Ministry of Science and Higher Education of the Russian Federation</institution></institution-wrap><institution-wrap><institution xml:lang="zh">Ministry of Science and Higher Education of the Russian Federation</institution></institution-wrap></funding-source><award-id>АААА-А21-121010690002-2</award-id></award-group></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Shaffer F, Ginsberg JP. 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