Cyclocondensation of methyl 5-methyl-1-(2-oxo-2-phenylethyl)-1H-pyrazole-3-carboxylate as a method for constructing a new 18-member nitrogenic macroheterocycle

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Abstract

A method for the synthesis of a new 18-m embered nitrogen macroheterocycle was developed. It was based on the acid-catalytic cyclocondensation of 1-[(2E,Z)-2-hydrazono-2-phenylethyl]-5-methyl-1H-pyrazole-3-carbohydrazide, a reaction product of methyl 5-methyl-1-(2- oxo-2-phenylethyl)-1H-pyrazole-3-carboxylate with hydrazine.

About the authors

A. O. Kharaneko

Litvinenko Institute of Physical Organic and Coal Chemistry

Email: antonhar08@rambler.ru
ul. R. Luxemburg, 70, Donetsk, 283114 Russia

T. M. Pekhtereva

Litvinenko Institute of Physical Organic and Coal Chemistry

ul. R. Luxemburg, 70, Donetsk, 283114 Russia

O. I. Kharaneko

Litvinenko Institute of Physical Organic and Coal Chemistry

ul. R. Luxemburg, 70, Donetsk, 283114 Russia

A. S. Morkovnik

Institute of Physical and Organic Chemistry, Southern Federal University

prosp. Stachki, 194/2, Rostov-on-Don, 344090 Russia

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