THE INDICES OF MORBIDITY OF PANCREAS CANCER IN WORKERS OF RADIATION DANGEROUS ENTERPRISE

Мұқаба

Дәйексөз келтіру

Толық мәтін

Аннотация

In Russia, during last decades increasing of morbidity of pancreas cancer is observed. This disease is among leading causes in the structure of mortality of malignant neoplasms. The data concerning effect of ionizing irradiation on development of pancreas cancer is ambiguous. The analysis was carried out concerning indices of morbidity of pancreas cancer in cohort of workers for the first time hired to enterprise of nuclear industry production association «Mayak» in 1948-1982 exposed to prolonged total external gamma-irradiation and internal alpha-irradiation by incorporated plutonium. It is established that in both considered cohort and total population, indices of morbidity of pancreas cancer depended on such non-radiation factors as attained age, gender, calendar period of observation, smoking and value of smoking index, alcohol abuse. The study established increasing of standardized by age indices of morbidity of pancreas cancer in workers exposed to prolonged external gamma-irradiation in doses 0.5 Gy and higher. The effect of internal alpha-irradiation on indices of morbidity of pancreas cancer was absent in examined cohort.

Авторлар туралы

G. Zhuntova

Southern Ural Institute of Biophysics

Хат алмасуға жауапты Автор.
Email: noemail@neicon.ru
Ресей

T. Azizova

Southern Ural Institute of Biophysics

Email: clinic@subi.su
Ресей

E. Grigor’Eva

Southern Ural Institute of Biophysics

Email: noemail@neicon.ru
Ресей

T. Zavarukhina

The central medical sanitary unit №71

Email: noemail@neicon.ru
Ресей

E. Fomin

The central medical sanitary unit №71

Email: noemail@neicon.ru
Ресей

Әдебиет тізімі

  1. Jemal A., Siegel R., Ward E., Hao Y., Xu J., Murray T. et al. Cancer statistics, 2008. CA Cancer J. Clin. 2008; 58(2): 71-96.
  2. Iovanna J., Mallmann M.C., Gonçalves A., Turrini O., Dagorn J.C. Current knowledge on pancreatic cancer. Front. Oncol. 2012; 2: 6.
  3. Каприн А.Д., Старинский В.В., Петрова Г.В., ред. Злокачественные новообразования в России в 2013 году (Заболеваемость и смертность). М: МНИОИ им. П.А. Герцена; 2015
  4. Vincent A., Herman J., Schulick R., Hruban R.H., Goggins M. Pancreatic cancer. Lancet. 2011; 378(9791): 607-20.
  5. Bosetti C., Lucenteforte E., Silverman D.T, Petersen G., Bracci P.M., Ji B.T. et al. Cigarette smoking and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (Panc4). Ann. Oncol. 2012; 23(7): 1880-8.
  6. Tramacere I., Scotti L., Jenab M., Bagnardi V., Bellocco R., Rota M. et al. Alcohol drinking and pancreatic cancer risk: a meta-analysis of the dose-risk relation. Int. J. Cancer. 2010; 126(6): 1474-86.
  7. Bosetti C., Rosato V., Li D., Silverman D., Petersen G.M., Bracci P.M. et al. Diabetes, antidiabetic medications, and pancreatic cancer risk: an analysis from the International Pancreatic Cancer Case-control Consortium. Ann. Oncol. 2014; 25(10): 2065-72.
  8. Maisonneuve P., Lowenfels A.B. Risk factors for pancreatic cancer: a summary review of meta-analytical studies. Int. J. Epidemiol. 2015; 44(1): 186-98.
  9. Klein A.P. Genetic susceptibility to pancreatic cancer. Mol. Carcinog. 2012; 51(1): 14-24.
  10. Ojajärvi I.A., Partanen T.J., Ahlbom A., Boffetta P., Hakulinen T., Jourenkova N. et al. Occupational exposures and pancreatic cancer: a meta-analysis. Occup. Environ. Med. 2000; 57(5): 316-24.
  11. Ozasa K., Shimizu Y., Suyama A., Kasagi F., Soda M., Grant E.J. et al. Studies of the mortality of atomic bomb survivors, Report 14, 1950-2003: an overview of cancer and noncancer diseases. Radiat. Res. 2012; 177(3): 229-43.
  12. Preston D., Ron E., Tokuoka S., Funamoto S., Nishi N., Soda M. et al. Solid cancer incidence in atomic bomb survivors: 1958-1998. Radiat. Res. 2007; 168(1): 1-64.
  13. Dropkin G. Reanalysis of cancer mortality in Japanese A-bomb survivors exposed to low doses of radiation: bootstrap and simulation methods. Environ. Health. 2009; 8: 56.
  14. Carr Z.A., Kleinerman R.A., Stovall M., Weinstock R.M., Griem M.L., Land С.E. Malignant neoplasms after radiation therapy for peptic ulcer. Radiat. Res. 2002; 157(6): 668-77.
  15. Boice J.D. Jr., Engholm G., Kleinerman R.A., Blettner M., Stovall M., Lisco H. et al. Radiation dose and second cancer risk in patients treated for cancer of the cervix. Radiat. Res. 1988; 116(1): 3-55.
  16. Little M.P., Stovall M., Smith S.A., Kleinerman R.A. A reanalysis of curvature in the dose response for cancer and modifications by age at exposure following radiotherapy for benign disease. Int. J. Radiat. Oncol. Biol. Phys. 2013; 85(2): 451-9.
  17. Travis L.B., Hauptmann M., Gaul L.K., Storm H.H., Goldman M.B., Nyberg U., et al. Site-specific cancer incidence and mortality after cerebral angiography with radioactive Thorotrast. Radiat. Res. 2003; 160(6): 691-706.
  18. Nyberg U., Nilsson B., Travis L.B., Holm L.E., Hall P. Cancer incidence among Swedish patients exposed to radioactive thorotrast: a forty-year follow-up survey. Radiat. Res. 2002; 157(4): 419-25.
  19. Polednak A.P., Stehney A.F., Lucas H.F. Mortality among male workers at a thorium processing plant. Health Phys. 1983; 4(Suppl. 1): 239-51.
  20. Cardis E., Vrijheid M., Blettner M., Gilbert E., Hakama M., Hill C. et al. The 15-country Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry: estimates of radiation-related cancer risks. Radiat. Res. 2007; 167(4): 396-416.
  21. Sokolnikov M.E., Gilbert E.S., Preston D.L., Ron E., Shilnikova N.S., Khokhryakov V.V. et al. Lung, liver and bone cancer mortality in Mayak workers. Int. J. Cancer. 2008; 123(4): 905-11.
  22. Azizova T.V., Day R.D., Wald N., Muirhead C.R., O'Hagan J.A., Sumina M.V. et al. The «clinic» medical-dosimetric database of Mayak production association workers: structure, characteristics and prospects of utilization. Health. Phys. 2008; 94: 449-58.
  23. Vasilenko E.K., Scherpelz R.I., Gorelov M.V., Stram D.J., Smetanin M.Y. External dosimetry reconstruction for Mayak workers. AAHP Special Session Health Physics Society Annual Meeting Paper. Salt Lake City; 2010. Available at: http://www.hps1.org/aahp/public/AAHP_Special_Sessions/2010_Salt_Lake_City/pm-1.pdf
  24. Dorrian M.D., Birchall A., Vostrotin V.V. Mayak Worker Dosimetry System (MWDS-2013): Phase I - Quality Assurance of Organ Doses and Excretion Rates from Internal Exposures of Plutonium-239 for the Mayak Worker Cohort. Radiat. Prot. Dosimetry. 2016; 1-16.
  25. Мерков А.М., Поляков Л.Е. Санитарная статистика (Пособие для врачей). М.: Атомиздат; 1975
  26. Blackford A., Parmigiani G., Kensler T.W., Wolfgang C., Jones S., Zhang X. et al. Genetic mutations associated with cigarette smoking in pancreatic cancer. Cancer Res. 2009; 69(8): 3681-8.
  27. Herreros-Villanueva M., Hijona E., Bañales J.M., Cosme A., Bujanda L. Alcohol consumption on pancreatic diseases. World J. Gastroenterol. 2013; 19(5): 638-47.
  28. Shuryak I., Hahnfeldt P., Hlatky L., Sachs R.K., Brenner D.J. A new view of radiation-induced cancer: integrating short- and long-term processes. Part II: second cancer risk estimation. Radiat. Environ. Biophys. 2009; 48(3): 275-86.
  29. Hunter N., Kuznetsova I.S., Labutina E.V., Harrison J.D. Solid cancer incidence other than lung, liver and bone in Mayak workers: 1948-2004. Br. J. Cancer. 2013; 109(7): 1989-96.
  30. Sokolnikov M., Preston D., Gilbert E., Schonfeld S., Koshurnikova N. Radiation Effects on Mortality from Solid Cancers Other than Lung, Liver, and Bone Cancer in the Mayak Worker Cohort: 1948-2008. PLoS One. 2015; 10(2): e0117784.

Қосымша файлдар

Қосымша файлдар
Әрекет
1. JATS XML
Жүктеу

© Zhuntova G.V., Azizova T.V., Grigor’Eva E.S., Zavarukhina T.P., Fomin E.P., 2020

Creative Commons License
Бұл мақала лицензия бойынша қолжетімді Creative Commons Attribution 4.0 International License.
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ:  ПИ № ФС77-50668 от 13.07.2012 г.