Synthesis, anti-inflammatory, analgesic and antyregifying properties of azomethine derivatives of the tetrahydropyrane series

作者: Isakhanyan A.U.¹, Hakobyan N.Z.¹, Muradyan R.E.¹, Tumadzhyan A.Y.¹, Panosyan H.A.¹, Harutyunyan A.A.¹
隶属关系:
1. The Scientific Technological Center of Organic and Pharmaceutical Chemistry NAS RA
期: 卷 61, 编号 5 (2025)
页面: 636-640
栏目: КРАТКОЕ СООБЩЕНИЕ
URL: https://hum-ecol.ru/0514-7492/article/view/692397
DOI: https://doi.org/10.31857/S0514749225050164
ID: 692397

如何引用文章

全文:

开放存取

开放存取

受限制的访问

##reader.subscriptionAccessGranted##
受限制的访问

受限制的访问

订阅或者付费存取

详细
作者简介
参考
补充文件
统计

详细

Azomethine derivatives of the tetrahydropyran series have been synthesized in a dry benzene by condensation of the corresponding amines with 4-chlorobenzaldehyde, 4-fluorobenzaldehyde, 4-(dimethylamino)-benzaldehyde, and thiophene-2-carbaldehyde. The anti-inflammatory, analgesic and antipyretic properties of the synthesized compounds have been studied.

关键词

azomethines, amines, condensation, tetrahydropyran series, anti-inflammatory activity, carrageenan and chronic inflammation

作者简介

A. Isakhanyan

The Scientific Technological Center of Organic and Pharmaceutical Chemistry NAS RA

Email: anush.isakhanyan.51@mail.ru
ul. Azatutyan, 26, Yerevan, 0014 Armenia

N. Hakobyan

The Scientific Technological Center of Organic and Pharmaceutical Chemistry NAS RA

ul. Azatutyan, 26, Yerevan, 0014 Armenia

R. Muradyan

The Scientific Technological Center of Organic and Pharmaceutical Chemistry NAS RA

ul. Azatutyan, 26, Yerevan, 0014 Armenia

A. Tumadzhyan

The Scientific Technological Center of Organic and Pharmaceutical Chemistry NAS RA

ul. Azatutyan, 26, Yerevan, 0014 Armenia

H. Panosyan

The Scientific Technological Center of Organic and Pharmaceutical Chemistry NAS RA

ul. Azatutyan, 26, Yerevan, 0014 Armenia

A. Harutyunyan

The Scientific Technological Center of Organic and Pharmaceutical Chemistry NAS RA

ul. Azatutyan, 26, Yerevan, 0014 Armenia

参考

Чиряпкин А.С., Кодониди И.П., Ларский М.В. Разработка и регистрация лекарственных средств. 2021, 10, 25–31. [Chiriapkin A.S., Kodonidi I.P., Lar- sky M.V. Drug Develop. Reg. 2021, 10, 25–31.] doi: 10.33380/2305-2066-2021-10-2-25-31
Кодониди И.П., Сочнев В.С., Терехов А.Ю., Сергеева Е.О., Рябухин И.Ю. Современные проблемы науки и образования. 2021, № 4. URL: https://science-education.ru/ru/article/view?id=31053 (дата обращения: 20.05.2022). [Kodonidi I.P., Sochnev V.S., Terekhov A.Yu., Sergeeva E.O., Ryabu- khin I.Yu. Modern problems of science and education. Surgery (ISSN – 2686-9101). 2021, № 4, p. 101–101.] doi: 10.17513/spno.31053.
Миронов А.Н., Бунятян Н.Д. и др. Руководство по проведению доклинических исследований лекарственных средств, часть 1, Министерство здравоохранения и социального развития РФ, ФГБУ Научный центр экспертизы средств медицинского применения, Москва, 2012.
European Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes. Strasbourg. No 123.18.03.1986. Directive 2010/63/EU of the European Parliament and of the Council of 22 September 2010 on the protection of animals used for scientific purposes.
Арутюнян Н.С., Акопян Л.А., Акопян Н.З., Пано- сян Г.А., Геворгян Г.А. ЖОрХ. 2011, 47 (1), 116–120. [Arutyunyan N.S., Akopyan L.A., Akopyan N.Z., Panosyan G.A., Gevorgyan G.A. Russ. J. Org. Chem. 2011, 47, 115–119.] doi: 10.1134/S1070428011010143

补充文件

附件文件

动作

1. JATS XML

版权所有 © Russian Academy of Sciences, 2025

TOP