REVISITED LOCALIZATION OF CAJAL CELLS IN SMOOTH MUSCLES OF DIFFERENT ORGANS
- Authors: Zashikhin AL1, Agafonov Y.V1, Lubeznova AY.1
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Affiliations:
- Northern State Medical University
- Issue: Vol 19, No 3 (2012)
- Pages: 56-58
- Section: Articles
- URL: https://hum-ecol.ru/1728-0869/article/view/17500
- DOI: https://doi.org/10.17816/humeco17500
- ID: 17500
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Abstract
Smooth muscle tissue represents a complicated and dynamical ensemble of smooth muscle cells characterized by different structural-methabolical parameters. In the composition of smooth muscle tissue a group of cell elements (cells of Cajal, ICC) is incorporated. Their structural organization and localization in smooth muscle tissue allow to consider them an important component of the system responsible for functional activity regulation. The goal of the study was to get a reliable technology for ICC isolation. The method of the alkaline cell dissociation was used. Isolated smooth cells of different organs were studied. Our findings have shown that the cells we have got by the method of cell dissosiation had clear stable morphological parameters of the interstitial cells of Cajal.
Full Text
Гладкая мышечная ткань представляет собой сложный и динамичный ансамбль мышечных клеток, характеризующихся различными структурнометаболическими параметрами.×
About the authors
A L Zashikhin
Northern State Medical UniversityArkhangelsk, Russia
Yu V Agafonov
Northern State Medical University
Email: chistjakovala@nsmu.ru
Arkhangelsk, Russia
A Yu Lubeznova
Northern State Medical UniversityArkhangelsk, Russia
References
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- Huanga Y., Meia F., Yua В., Zhanga Н., Hana J. Distribution of the interstitial Cajal-like cells in the gallbladder and extrahepatic biliary duct of the guinea-pig. J. Fcta histochemica. 2008; 11 1: 157-165.
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- Johnston L., Woolsey S., Cunningham R., O’Kane H., Duggan B., Keane Р. Morphological Expression of KIT Positive Interstitial Cells of Cajal in Human Bladder. The journal of urology. July 2010; 184: 370-377, 725-733.
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- Takaki M. Gut Pacemaker Cells: the Interstitial Cells of Cajal (ICC). J. Smooth Muscle Res. 2003; 39 (5): 137161.