Vol 19, No 11 (2012)

New realias into which the mankind ran in the twenty first century are characterized by a tremendous upgrowth of science, techniques, information technologies and are accompanied by economical and social perturbations. They demand brand new views of the environment, the man and the society. In the article, the necessity to use a holistic approach in the system of general knowledge, especially in biology and medicine, has been grounded.

During a hygienic, psychological and physiological complex study, objective interrelationships between modern office workers work intensity and psychological, as well as the cardio-vascular and the central nervous system functional state changes, have been established. These changes indicated occupational stress development against mental work intensity increase. A complex of methods (including computer programs of psychological tests) for occupational stress manifestations detection at the prenosological stage and prevention have been selected.

Among apparently healthy persons, there has been carried out a thermographical study of hands and a computer analysis of the heart rhythm variability before and after a cold test. It has been established that detected in persons aged 20—30 years convection-type heat transmission from terminal phalanges by blood stream from finger arteries to superficial vessels during not less than 10 minutes in case of domination of activity of the parasympathetic nervous system (PNS) indicated good compensatory reactions of the vascular system. The most spread among the persons over 50 and older of the contact way of heat transmission in forearms from warm zones to cold zones during 22 minutes and more in case of domination of activity of the parasympathetic nervous system was indicative of cold deadaptation.

Aim: Assessment of influence of the combined oral contraceptives, taking into account estrogen doses and duration of the preparation use, on condition of the homeostasis system in women at reproductive age in the population of Arkhangelsk. Methods: A cross-sectional clinical-laboratory study of influence of the combined oral contraceptives on the homeostasis system has been carried out. Results: Statistically significant distinctions were received as an indicator of activated partial thromboplastin time (р = 0.002), that testified a tendency to hypercoagulation in the women taking the combined oral contraceptives in comparison with the control group.

Purpose of study. Estimation of efficiency of application of BIOPTRON phototherapy for treatment of placental insufficiency (PI) in pregnant women with 1 type diabetes mellitus (DM1) in conditions of ecological trouble. Methods. Two groups of supervision were formed: the I group - 42 pregnant women with DM1 who received phototherapy “BIOPTRON”; the II group - 57 pregnant women with DM1 who did not receive phototherapy (the control group). Efficiency of the carried out therapy was estimated with the use of the markers of blood serum morphology. All received materials were subjected to statistical processing with given reliability 95 % or significance value (p) 0.05. Results and conclusions. In the 1-st group of the women with DM1, the outcomes of pregnancy were more favorable both for the mothers and for the fetuses. Almost 7 times less often, pregnancy was terminated in the second trimester (p < 0.01 less often), premature births occurred 2 times less often, diabetic fetopathy developed 3.3 times less often as well as fetus chronic intrauterine hypoxia, placental insufficiency occurred 2 times less often (OR - 0.42, RRR - 76 %, NNT - 1.31). Pregnancies complicated with heavy forms of toxemia of pregnancy occurred also much less often (OR — 0.12, 95 % CI 0.06 — 0.2, p = 0.003) in comparison with the control group. Outcomes of the deliveries of the pregnant women with DM1 receiving phototherapy indicated positive influence of light waves BIOPTRON on homeostasis.