Vol 22, No 10 (2015)

A prospective study of thyroid function in 112 women of the second generation descendants, ancestors of whom were in the area of radiation effects of the Semipalatinsk test site 29 August 1949. In retrospect, thyroid disease was studied in progenitors (233 women exposed to radiation) and parents - the descendants of the first generation (247 women). The control group included women not exposed to radiation and radiation lived outside the track. Retrospective analysis phase included archival documents and conducted with historical controls. Prospective phase included a study of the type "case - control". The state of the thyroid gland and its hormone profile, gorrmony pituitary. It was found that women who were in the area of radiation exposure, thyroid disease is more common, in contrast to the control group (8,2 ± 0,2) and (2,1 ± 0,3) %; p = 0.046, they are characterized by the presence of hyperthyroidism, hypothyroidism, postoperative (not excluded surgery for thyroid cancer), autoimmune thyroiditis, thyroid cancer. Among women, the first generation descendants of thyroid disease met by 68.3 % more than in the control group (p = 0.014), but as women of the second generation offspring. In women, the second-generation descendants greatly increased in the structure of the thyroid gland pathology share of autoimmune thyroiditis (11.6 %; p = 0.039), which was not observed in their parents and grandparents. Thus, the high incidence of thyroid disease is characterized by both women exposed to radiation, and their descendants in the first and second generation.

A mental pandemy of psychosomatoses is consistently developing in singular and stress-producing reality. There has been proposed a synergetic biopsychosociospiritual conception of epidemic psychosomatic disorders, including three prenosological fractals of development: predisposition - a psychosomatogenic family, latent - psychovegetative diathesis, initial - a functional disorder, and three nosological fractals: a full-scale clinical picture - a mental epidemic, chronization - a destructive mental epidemic, an outcome - a pandemy. There has been grounded a block-modular approach to development of multidisciplinary programs and patient-specific medical-preventive routes of mental medicine. Its mission consists in adaptive engineering and management of consciousness and health. Its enables to plan and reconstruct mental immunity as the matrix of identity and security base.

Objective: To study the dynamics of socio-psychological climate and mood of the team, a functional status of an expedition members during an Arctic voyage. Methods: psychological testing, observation. Type of study: observational, descriptive. Sample: members of the expedition "Arctic Floating University 2013", 38 people. Statistical methods: descriptive statistics, ANOVA with repeated measurements, the Friedman χ 2- criterion. Conclusions: 1. Knowledge of the features of the expedition team members composing the group formed for the first time increased from the beginning to the end of the voyage. 2. The expedition duration (25 days) was not sufficient for the team to reach the stage of functional-role correlation. Development of the group unity did not significantly affect the team mood due to the onset of fatigue because of communication and work in monotonous conditions. 3. The features of the change of the expedition members' functional status were as follows: the delayed lowering of self-rating of the states (initially human condition itself worsened); the phase of reversing trends preceded the phase of resource use optimization; the phase of "waiting for the voyage end" was separated; during the voyage, specially arranged emotional events affected the participants' self-rating of the functional states; the changes in the states during the voyage did not have a large amplitude, in their manifestation was not extreme.

In the contemporary world one of the leading causes of death and disability of the population belongs to the stroke. The average frequency of death within the first 30 days after stroke varies from 17 % to 34 %. During the first year about 50 % of patients die. Only 20 % of stroke survivors recover completely, while 80 % of these patients are permanently disabled. Along with the issues of stroke's prevention, treatment and its rehabilitation, it is a relevant aspect to predict the outcome of the patient in the post-stroke condition. It is known that the timely prediction of the cerebral stroke's outcome allows to avoid patient's death and to reduce the neurological deficit in case of correct appointment. Predictive models and scales are the simplest and most accessible instrument for estimating the patient's condition and predicting the outcome after stroke. Despite a considerable quantity of studies in this area the problem of forecasting the stroke's outcome is still relevant. Over the past 10 years the predictive value of some clinical scales has been further investigated, new information about biomarkers has been obtained, whose appearance in the blood correlates with the outcome of stroke, and which could potentially be used in predictive models. The information is not always available for physicians and researchers because of the presence of fragmentation and a language barrier. So the aim of this systematic review was analyzing and combining the available information of the methods predicting the stroke's outcome in the past 10 This review article presents an analysis of methods predicting the outcome in patients after stroke. The study included full-text publications in the English language for the last 10 years, describing the scales or models predicting the post-stroke's outcome in patient. We studied 668 sources in databases MEDLINE, SCOPUS, describing the clinical scales or prediction models that use serum biomarkers as predictors. After screening, 35 articles were selected and included in the analysis.