Vol 20, No 9 (2013)

The article has described an urgent current problem of changes in environmental quality on the Siberian developed territories. The original materials illustrating the problem have been represented using an example of industrial development of the Priangarsk districts of the Irkutsk Oblast and the Krasnoyarsky Krai. The relative risk of children’s morbidity in the zones of the aluminum production increases by 1.4-1.7 times based on the materials of the social-hygienic monitoring, the nature observations and the results of the numerous experiments using mathematical models. The experience obtained is recommended to be taken into account in preparing programs of social-economic development of the northern regions of Siberia.

With the goal to establish a direct effect on resiliency of organisms’ cells, there was studied the effect of garlic preparation Phytoncidin on growth of mice’ kidney tissue cells in their cultivation in growth medium 199 with fetal serum and without it. It has been established that in the set span of concentrations, Phytoncidin delayed formation of cell colonies and their growth all the way to a complete stop of their formation.

The electron-microscopic analysis of experimental animals’ eye tissues has shown that toxic effects of a diesel engine’s exhaust gases caused angiopathy and increased vascular permeability. In-parallel, there were formed compensatory-adaptive mechanisms, such as changes in the structure of the epithelium and fibroblasts. A crystallographic picture also changed: the rays extending from the center of crystallization became thin and fragmented.

The analysis of the results of the dynamics of processes of marriages and divorces has been represented in this paper and the population reproductive intentions in the Irkutsk Region have been characterized. The study materials testify an increased (from the beginning of 2000s) number of registered marriages and a high level of divorces (during 2007-201 1, the average index was 554.0 divorces per 1 000 marriages). About 40 % of children were born in “civil marriages” (unregistered marriages) or by single mothers each year in the region. The profound sociological studies of youth groups and adult population living in the towns of the Irkutsk Region have shown that most of the respondents were oriented towards formation of families with not many children. Among the interviewed “family” respondents, 64.5 % had one child, and 31.4 % had two children. Among the main causes preventing from realization of their reproductive intentions, the respondents noted financial and housing problems.

Microbiocenosis of the intestine and activity of hydrolytic enzymes in saliva and feces of infants treated with antibiotics have been studied. It has been established that 100 % of the examined children had intestinal dysbacteriosis of different degrees. After a course of treatment with traditional dry probiotics and liquid synbiotics with pectin, positive dynamics in restoration of the disturbed microflora was observed. It has been shown that during an analysis of dysbacteriosis correction effectiveness, it is desirable to carry out enzymological assessment of feces, which presents dynamics of restoration of functional activity of the intestinal normal flora.

The current state of knowledge on the contribution of certain trace element balance disturbances (TEBD) to ecologically-induced human disorders has been reviewed in the article. Our own research on the TEBD effects on human reproductive function has been described in brief. The considered research has shown urgency of determination of not only the total biosubstrate content of chemical elements, but also of their concentrations’ correlations. The issue of introduction of “bioinorganic” diagnostics into common clinical and epidemiological practice, especially for ecologically problematic areas, has been discussed.