Vol 22, No 11 (2015)

The article has introduced the examination results of apparently healthy men (n=27), who were born and permanently lived in the European North of Russia. The work objective was to discover peculiarities of the cardiovascular system response to local hand and foot skin cooling of the men. The preload rates of the cardiac muscle contractility, the afterload rates of functioning of the left ventricle and the rates characterizing hemodynamic status have been determined with the help of the hardware and software complex «Integrated Monitoring System SYMONA 111». The initial indexes and the indexes just after cold stress (dipping a hand into a vessel with cold water at temperatures of 24, 15, 8 °С) were registered. The same method and the same temperatures were used to cool feet. It has been shown that local hand and foot skin cooling caused a significant rise in the preload rates, the cardiac muscle contractility, the afterload functioning of the left ventricle, arterial pressure, and decreased the heart rate. During the hemodynamics indices analysis, the highest responsiveness of the cardiovascular system was registered after the local hand skin cooling in water at 15 0С, the lowest - in water at 24 0С. More pronounced changes occurred during the foot cooling.

In the period from March 2013 to May 2014, in order to study the syndrome of ischemia-reperfusion and immediate treatment results, a prospective non-randomized clinical study of 43 patients with infrarenal abdominal aortic aneurysm (AAA) was realized. The patients, depending on the method of treatment, divided into 2 groups: 26 patients with open repair (OR) and 17 patients with endovascular repair (EVAR). The main criteria for inclusion into the study were AAA of II and III type by A. V. Pokrovsky and elective repair of the AAA. As markers of ischemia-reperfusion C-reactive protein, proinflammatory cytokine IL-6, anti-inflammatory cytokine IL-10 and oxidative status were investigated. The level of ischemic inflammation and reperfusion markers in patients with OR was generally higher than in patients with EVAR, and the level of IL-6 excess was statistically significant (p = 0.001). The longer the time compression of the abdominal aorta in the OR the higher the level of markers of ischemia-reperfusion. In patients with a time compression of the abdominal aorta more than 30 minutes there was a significant excess of IL-6 before removing the clamp from the abdominal aorta (p = 0.035) and after the start of the magistral blood flow to both lower extremities (p = 0.050), as well as significant excess of indicator of oxidative status of the blood Oxystat before removing the clamp from the abdominal aorta, after the launch of the main blood flow to the feet and 30 minutes after the end of surgery (p = 0.001). The number of local and systemic complications at the early postoperative period was significantly higher in patients undergoing OR (p = 0.002), which for this indicator shows the benefits of EVAR.

The results of research of some psychological and psychophysiological indicators of students of various social groups (orphan students and students from usual families) in the course of adaptation to university training have been presented. Assessment of psychophysiological parameters was carried out with application of the standardized, approved techniques (A. Bass and A. Darki's technique adapted by A. K. Osnitsky: attention assessment, a test for noise stability). The conducted research has revealed reliable differences in psychophysiological characteristics of the students from various social groups. "Verbal aggression", "sense of guilt" and "the aggression index" were significantly lower (by 10.0; 25.0 and 4.5 % respectively) in the orphan students in comparison with the girls from the usual families. Psychophysiological tests "Attention assessment" and "Noise stability" have revealed a low degree of noise stability in the examined girls of both groups. "Physical" and "indirect aggression" were significantly higher in the orphan students. The test "Noise stability" has identified lower indicators of response time in the orphan students (by 7 %) and the system lower functional level (by 8 %). The correlation analysis has shown the nature of the interrelation of noise stability and the students' individual and psychological features. The received results demonstrate the necessity of the students' adaptation processes monitoring for timely arrangement of medical-preventive actions.

In the article, there have been analyzed the basic principles of contemporary science in study of the problem of culture code stability of the northern indigenous minorities which development was strongly influenced by the factors like nature and climate, namely by extreme conditions of human life and activity. This problem is important today as preservation of culture of the northern indigenous small ethnic communities and in fact their preservation as social, and cultural phenomena of the human civilization is of an ethic, scientific and practical interest. The authors proceeded from the assumption that the spiritual and material life of these minorities was based on the principles of "the ecological imperative" (the term is offered by the Academician N. N. Moiseev for designation of ethic content of human-nature interactions at the stage when the ecological crisis threatens the mankind). The authors have proposed to understand the reasons for sustainability of all the spheres of the minorities life under growing pressure of the external civilization by using an analysis of different culture phenomena, which are similar among the ethnic groups living independently on the vast territories and have no opportunity to communicate. That kind of culture "texts" reveals the process of human adaptation not only to the survival but also to the full value life under the conditions that are severe for representatives of other cultures.