No 11 (2019)

Articles
ELEMENTAL COMPOSITION OF HUMAN HAIR IN NORTH-WESTERN SIBERIAN CITIES WITH DIFFERENT DRINKING WATER QUALITY
Minyailo L.A.
Abstract
The aim of the study was to assess elemental composition of hair of residents of the Khanty-Mansiysk Autonomous Okrug (Khanty-Mansi Autonomous Okrug) living in cities with different quality of drinking water. Methods. The elemental composition of hair was studied in 84 residents of Surgut and Khanty-Mansiysk cities with high-quality drinking water water, and in 71 residents of Nefteyugansk and Nyagan - cities with low-quality drinking water. The concentration of 25 chemical elements in the hair including iron (Fe), manganese (Mn), calcium (Ca), magnesium (Mg), copper (Cu), zinc (Zn) and selenium (Se) was assessed using atomic emission spectroscopy (AES-ICP) and mass spectrometry (MS-ICP) with inductively coupled argon plasma on Optima 2000 DV and ELAN 9000 instruments at the INPO "Center for Biotic Medicine" (Moscow). Data were analyzed using MS Excel and STATISTICA 8.0. Results. Significantly higher concentrations of Fe and Mn (p < 0,001) and lower concentrations of Se (p = 0,012) were revealed in the hair of residents of cities with low-quality drinking water. The concentration indices of Ca, Mg, and Cu in all cities were similar. The prevalence of Zn and Se deficiency in cities with low-quality drinking water was 1.5 and twice as high compared to areas with high quality drinking water. Conclusions. Residents of cities with low quality drinking water have less favourable concentrations of studied elements in hair. This may be associated with lower antioxidant protection which in turn may be associated with greater prevalence of chronic diseases in these cities.
Ekologiya cheloveka (Human Ecology). 2019;(11):4-11
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AIR QUALITY AND CHILDREN’S HEALTH: THE ROLE OF INCREASING TRANSPORT-RELATED AND THERMAL AIR POLLUTION
Chanchaeva E.A., Gvozdareva O.V., Gvozdarev A.Y.
Abstract
We performed a literature review on the associations between quality with special emphasis on increasing transport and thermal air pollution. Motor vehicles and coal boilers are the main anthropogenic sources of emissions of pollutants into the air. Attempts to reduce their content in the air currently do not bring the desired result, the exhaust of internal combustion engines and combustion products of solid fuel remain the main polluting factors. Air quality in residential areas is influenced by climatic and natural peculiarities of the regions (weather, terrain, etc.). Respiratory diseases, including acute respiratory infections and chronic obstructive pulmonary disease, cardiovascular diseases, lung cancer are significantly associated with air pollution in adults. A child's body is highly sensitive to the environmental factors which allows us to consider children's health as an indicator of the state of the environmental pooluiton. The deterioration of the ecological state of the air environment in Gorno-Altaisk (Altay region of Russia) is associated with increasing transport load, solid fuel stationary sources, and transport of pollutants from neighboring regions. Air pollution in the region needs to be monitored and addressed. This requires zoning of residential areas according to the degree of air pollution and analysis of the health of children as the most vulnerable part of the population, taking into account the environmental situation.
Ekologiya cheloveka (Human Ecology). 2019;(11):12-19
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CHANGES IN CENTRAL HEMODYNAMICS AFTER LOCAL SKIN COOLING IN FEMALES
Korobitsyna E.V., Gudkov A.B., Popova O.N.
Abstract
Aim: we studied changes in central hemodynamics after localized cold exposure in females aged 17-20 years. Methods: We exposed the skin (hand and foot) of female to water at temperatures 24, 15 and 8 degrees Celsius. SIMONA 111 Integrated Monitoring System was used to assess indicators of preload, myocardial contractility, afterload, left ventricular function and hemodynamic status indicators Results. The hand cooling with water at a temperature of 15 and 8 degrees Celsius decreased inotropy index by 6.3 % (p = 0.012) and 8.2 % (p = 0.007), respectively. Corresponding reductions in myocardial contractility index were 2.5 % (p = 0.033) and 1.5 % (p = 0.010), in myocardial stress coefficient - by 6 % (p < 0.001) and 5.4 % (p = 0.002), respectively), and the cardiac index of the work of the left ventricle - by 7.0 % (p = 0.003) and 8.0 % (p = 0.002). Foot cooling at 24 degrees Celsius decreased myocardial contractility index by 1.5 % (p = 0.031) and myocardial stress coefficient by 7.4 % (p = 0.025)), while exposure to 15 and 8 degrees Celsius (decreased notropy index by 12.1 % (p = 0.002) and by 14.7 % (p = 0.003), myocardial contractility index by 7.6 % (p < 0.001) and 10.2 % (p <0.001), respectively). Cardiac index of the work of the left ventricle decreased by 3.5 % (p = 0.007) following foot exposure to 24 degrees Celsius. Mean blood pressure increased by 4.2 % (p = 0.013) following exposure to 8 degrees Celsius. Conclusions. Local cold exposure leads to a decrease in myocardial contractility and left ventricular function and to an increase in hemodynamic status. The greatest reactivity of the cardiovascular system is stated after local cooling of the foot skin in water at a temperature of 15 and 8 degrees Celsius.
Ekologiya cheloveka (Human Ecology). 2019;(11):20-23
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PSYCHOSOMATIC DIATHESIS AS AN ANTICIPATION OF A “MENTAL CODE” OF FATE
Sidorov P.I.
Abstract
The rapid growth of the mental epidemic of psychosomatic disorders in the modern world with constituting from 20 to 60 % of medical conditions warrants further search for new approaches to etiopathogenesis, its course, treatment and prevention. A new synergetic biopsychosocial spiritual methodology of mental medicine (MM) can significantly expand the multidisciplinary capabilities of prenosological screening and forecasting, individualization of routes and assistance programs. The concept of mental immunity (MI) as a matrix of identity and interface of consciousness is grounded. For a generalized characteristic of the continuum of qualitative mental states modulated by MI functions, the term "menom" is proposed. «Epimenom» accumulates acquired peculiarities of MI. Functional pleiotropy of MI is described. Systematic disorders of MI functions as a "mental code" of consciousness and identity, which make up the clinical phenomenology of nonspecific mental immunodeficiency syndrome (SMID) in psychosomatic diathesis, are systematized. The priority task of primary prevention of diathesis is to increase the resources of MI and the registers of mental resilience of the psychosomatogenic family. An emergent rule of the "four keys" of sanogenetic therapy is proposed.
Ekologiya cheloveka (Human Ecology). 2019;(11):24-27
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ASSESSMENT OF THE EFFICIENCY OF PROACTIVE BEHAVIOR TRAINING AND INDIVIDUAL PSYCHOTHERAPY AMONG PERSONS WITH DIFFERENT DEGREES OF PROFESSIONAL BURNOUT
Slabinskiy V.Y., Voishcheva N.M., Neznanov N.G., Nikiforov G.S., Ulyanov I.G., Kharkova O.A.
Abstract
The aim of the study is to assess the effectiveness of proactive behavior training and individual psychotherapy among groups with low/medium and high/extremely high level of professional burnout (PB). Methods. The sample consisted of 146 individuals (100 women and 46 men) who underwent proactive behavior training in Saint Petersburg, Tver, Moscow and Vladivostok. Group I included 73 persons with low or medium PB, 20 of them had an additional course of individual positive dynamic psychotherapy; Group II consisted of 73 individuals with high or extremely high PB, 25 of them had additional course of individual positive dynamic psychotherapy. Methods: Zimbardo Time Perspective Inventory (ZTPI); Maslach Burnout Inventory (MBI); Proactive Coping Inventory (PCI); and LHC Conflict. Mann-Whitney test was used to compare average values. Asociations between categorical variables was searched using Pearson x2 test. Associations between binary outcome and three independent variables were studied using multivariable logistic regression. Results: The positive impact of proactive behavior training on the individual typological characteristics of the personality was revealed; moreover, in the group of people with a high/extremely high level of PB compared with subjects with a low/medium level, statistically significant improvements were observed in the following parameters as "Strategic planning" (p = 0.019), "Search for emotional support" (p = 0.016), "Emotional exhaustion" (p = 0.081), "Depersonalization" (p = 0.001) and "Reduction of professional achievements" (p = 0.002). Conclusion: The course of individual positive dynamic psychotherapy in addition to proactive behavior training has a positive effect on the "Reflexive Overcoming", "Strategic Planning", "Search for Emotional Support", and negative effect on the "Depersonalization", and "Reduction of Personal Achievements".
Ekologiya cheloveka (Human Ecology). 2019;(11):28-34
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INCIDENCE OF CONGENITAL MALFORMATIONS AMONG NEWBORNS IN ECOLOGICALLY UNFAVORABLE TERRITORIES OF THE BRYANSK REGION (2000-2017)
Korsakov A.V., Geger E.V., Lagerev D.G., Pugach L.I.
Abstract
The aim of the study was to assess the incidence congenital malformation of congenital malformations in newborns in territories of the Bryansk region with different levels of radioactive, chemical and combined environmental pollution using official statistics for the period 2000-2017. Methods: Shapiro-Wilk test, White test, Wilcoxon T-test, Spearman rank correlation test and regression models were used to study associations between radioactive, chemical and combined pollution and the incidence of congenital malformations in the region and prognosis using the inverse relationship. Results. The incidence of polydactyly, multiple congenital malformations and the amount of de novo birth defects in newborns is significantly lower in the most ecologically favorable districts than in areas with radiation, chemical and combined pollution. For polydactyly - at the level of significance (p), 0.003-0.023 (decrease by 4.7-7.4 times), for the amount of multiple congenital malformations - 0.001-0.054 (2.5-6.8 times) and for amount of de novo birth defects - 0.0010.007 (3.5-4.6 times). Statistically significant differences were found in the incidence of multiple congenital malformations in the conditions of combined pollution in comparison with similar indicators in the territories of radioactive (2.2 times, p = 0.034) and chemical (1.9 times, p = 0.008) pollution (values 1.48; 0.67 and 0.78). A decrease in the long-term trend of frequency of multiple congenital malformations in the period 2000-2017 was revealed on the territories of combined pollution, and increase - on territories of radioactive and chemical pollution. Nevertheless, the predicted values of the frequency of multiple congenital malformations on the territories of combined pollution by 2018-2023 will significantly (p = 0.027) exceed the indicators of the territories of radioactive and chemical pollution by 39.6 and 45.7 % (values 1.18; 0.845; 0.81). Conclusions. Our results suggest synergistic effect of radiation and chemical pollution on the incidence of multiple congenital malformations.
Ekologiya cheloveka (Human Ecology). 2019;(11):35-47
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PREVALENCE AND PROGNOSTIC SIGNIFICANCE OF DYSGLICEMIA IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AT THE STAGE OF DECOMPENSATION OF CHRONIC CARDIAC FAILURE
Ishekova M.Y., Dvoryashina I.V., Kholmatova K.K., Grjibovski A.M.
Abstract
The aim was to study the prevalence of dysglycemia and glycemic variability (GV) during hospitalization for chronic heart failure (CHF) decompensation and their effect on four-years survival. Methods: A retrospective analysis of the hospital records of 279 patients with type 2 diabetes mellitus (DM), hospitalized with CHF decompensation to the First City Clinical Hospital in Arkhangelsk was performed. Mann - Whitney tests were used for numeric variables. Simple and multiple logistic regression analyses were used to determine the effect of glycemia at admission, GV indicators on the early and long-term prognosis. Results: Median blood glucose at hospitalization was 8.80 (6.74; 11.04) mmol/l. Off-target glycemia was observed in 245 (87.8 %) patients. More than half of the measured tests during hospitalization had glycemic values beyond the recommended levels for the hospitalization period (82.6 %). In patients who died in the long-term period (n = 64, 28.1 %), hyperglycemia of more than 10.0 mmol/l was observed in 43.8 % of the measured tests during hospitalization, in 18.3 % - hyperglycemia from 7.8 to 10.0 mmol/l. Patients who died in the long-term period had higher indices of GV in comparison with the survivors (p = 0.004 for glycemic level variation, p = 0.008 for standard deviation and p = 0.001 for variation coefficient). High GV was associated (OR: 1.943; CI 1.013-3.725, p = 0.046) with the outcome, regardless of gender, manifestations of heart failure and renal function. Conclusions. Altogether, 87.8 % of patients had dysglycemia during the period of hospitalization. High GV during hospitalization was observed in 50.2 % of patients. High GV during hospitalization is an independent risk factor for for-years mortality
Ekologiya cheloveka (Human Ecology). 2019;(11):48-54
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ENDOECOLOGICAL REHABILITATION AND TREATMENT OF ONCOLOGICAL PATIENTS AT A RESORT: A LITERATURE REVIEW
Khodasevich L.S., Khudoev E.S., Naslednikova I.O., Khodasevich A.L.
Abstract
This literature review provides an overview of endoecological rehabilitation and treatment of oncological patients using Yu. M. Levin's method, in which the maintenance of metabolic homeostasis is achieved by combined or sequential stimulation of interstitial humoral transport and lymphatic drainage by various types of exposure. We present current understanding of the relationship between endointoxication syndrome and cancer and its complications and provide background for the use of endoecological rehabilitation in oncology. So far, this method is not widely used in medical practice among cancer patients due to contraindications. In recent years, interest in the potential of physiotherapy in the treatment of neoplasms has increased. Endoecological rehabilitation and treatment is carried out using specially selected herbal medical products and original physiotherapeutic procedures. In sanatorium-resort conditions, the latter replace natural physical factors, which seem to be more effective and have a wider range of effects than a similar set of instrumental physiotherapy.
Ekologiya cheloveka (Human Ecology). 2019;(11):55-64
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