Vol 26, No 11 (2019)

We performed a literature review on the associations between quality with special emphasis on increasing transport and thermal air pollution. Motor vehicles and coal boilers are the main anthropogenic sources of emissions of pollutants into the air. Attempts to reduce their content in the air currently do not bring the desired result, the exhaust of internal combustion engines and combustion products of solid fuel remain the main polluting factors. Air quality in residential areas is influenced by climatic and natural peculiarities of the regions (weather, terrain, etc.). Respiratory diseases, including acute respiratory infections and chronic obstructive pulmonary disease, cardiovascular diseases, lung cancer are significantly associated with air pollution in adults. A child's body is highly sensitive to the environmental factors which allows us to consider children's health as an indicator of the state of the environmental pooluiton. The deterioration of the ecological state of the air environment in Gorno-Altaisk (Altay region of Russia) is associated with increasing transport load, solid fuel stationary sources, and transport of pollutants from neighboring regions. Air pollution in the region needs to be monitored and addressed. This requires zoning of residential areas according to the degree of air pollution and analysis of the health of children as the most vulnerable part of the population, taking into account the environmental situation.

The rapid growth of the mental epidemic of psychosomatic disorders in the modern world with constituting from 20 to 60 % of medical conditions warrants further search for new approaches to etiopathogenesis, its course, treatment and prevention. A new synergetic biopsychosocial spiritual methodology of mental medicine (MM) can significantly expand the multidisciplinary capabilities of prenosological screening and forecasting, individualization of routes and assistance programs. The concept of mental immunity (MI) as a matrix of identity and interface of consciousness is grounded. For a generalized characteristic of the continuum of qualitative mental states modulated by MI functions, the term "menom" is proposed. «Epimenom» accumulates acquired peculiarities of MI. Functional pleiotropy of MI is described. Systematic disorders of MI functions as a "mental code" of consciousness and identity, which make up the clinical phenomenology of nonspecific mental immunodeficiency syndrome (SMID) in psychosomatic diathesis, are systematized. The priority task of primary prevention of diathesis is to increase the resources of MI and the registers of mental resilience of the psychosomatogenic family. An emergent rule of the "four keys" of sanogenetic therapy is proposed.

The aim of the study was to assess the incidence congenital malformation of congenital malformations in newborns in territories of the Bryansk region with different levels of radioactive, chemical and combined environmental pollution using official statistics for the period 2000-2017. Methods: Shapiro-Wilk test, White test, Wilcoxon T-test, Spearman rank correlation test and regression models were used to study associations between radioactive, chemical and combined pollution and the incidence of congenital malformations in the region and prognosis using the inverse relationship. Results. The incidence of polydactyly, multiple congenital malformations and the amount of de novo birth defects in newborns is significantly lower in the most ecologically favorable districts than in areas with radiation, chemical and combined pollution. For polydactyly - at the level of significance (p), 0.003-0.023 (decrease by 4.7-7.4 times), for the amount of multiple congenital malformations - 0.001-0.054 (2.5-6.8 times) and for amount of de novo birth defects - 0.0010.007 (3.5-4.6 times). Statistically significant differences were found in the incidence of multiple congenital malformations in the conditions of combined pollution in comparison with similar indicators in the territories of radioactive (2.2 times, p = 0.034) and chemical (1.9 times, p = 0.008) pollution (values 1.48; 0.67 and 0.78). A decrease in the long-term trend of frequency of multiple congenital malformations in the period 2000-2017 was revealed on the territories of combined pollution, and increase - on territories of radioactive and chemical pollution. Nevertheless, the predicted values of the frequency of multiple congenital malformations on the territories of combined pollution by 2018-2023 will significantly (p = 0.027) exceed the indicators of the territories of radioactive and chemical pollution by 39.6 and 45.7 % (values 1.18; 0.845; 0.81). Conclusions. Our results suggest synergistic effect of radiation and chemical pollution on the incidence of multiple congenital malformations.

This literature review provides an overview of endoecological rehabilitation and treatment of oncological patients using Yu. M. Levin's method, in which the maintenance of metabolic homeostasis is achieved by combined or sequential stimulation of interstitial humoral transport and lymphatic drainage by various types of exposure. We present current understanding of the relationship between endointoxication syndrome and cancer and its complications and provide background for the use of endoecological rehabilitation in oncology. So far, this method is not widely used in medical practice among cancer patients due to contraindications. In recent years, interest in the potential of physiotherapy in the treatment of neoplasms has increased. Endoecological rehabilitation and treatment is carried out using specially selected herbal medical products and original physiotherapeutic procedures. In sanatorium-resort conditions, the latter replace natural physical factors, which seem to be more effective and have a wider range of effects than a similar set of instrumental physiotherapy.