Vol 23, No 9 (2016)

Problems of drinking water quality in Birobidzhan are considered. The topical issue is its deferrization. It has been noted that drinking water in Birobidzhan is characterized by the naturally caused low content of biogenic elements such as calcium and magnesium. The objectives of the current work are: 1. to investigate the influence of an ion-exchange deferrization of drinking water in Birobidzhan on Ca2+, Mg2+ concentration and the total hardness of water index, 2. to analyse physiological adequacy of this water. Photometric and titrimetric methods have been used to settle alimony of the total iron, calcium, magnesium and the total hardness of water index drinking water tests. It has been testified that the total iron concentration in two groups of tests is higher than maximum marginal value and is 0.51±0.04 mg/dm3 and 1.92±0.14 mg/dm3. Water purification by means of household filters and its deferrization by cation exchange resin KU-2-8chS and cation exchange resin Purolite C100E resulted in reduction of the total iron concentration with value lower than maximum allowable concentration. However, calcium and magnesium concentrations considerably decreased after deferrization as well, from initial C(Ca2+) = 16.31±1.79 mg/dm3 and C(Mg2+) = 4.67±0.70 mg/dm3, to C(Ca2+) = 3.19±0.48 mg/dm3 and C(Mg2+) = 1.21±0.30 mg/dm3. The total hardness decreased from 0.84±0.08 mg-equivalent/dm3 to 0.13±0.01 mg-equivalent/dm3. The study showed physiological inadequacy of such low harness drinking water.

Smoking is one of the risk factors in the disturbance development in the "mother-placenta-fetus" system which serves as one of the major preventable factors of pregnancy unsuccessful outcome for both mother and fetus. In order to identify characteristics of hemodynamic status of "mother-placenta-fetus" system in smoking pregnant women the analysis of physiological indicators of Doppler ultrasound had been done by means of the of uteroplacental, fetoplacental and fetal blood flow assessment. The study included 120 pregnant women of Northern Medical Clinical Center named after N. A. Semashko of Russian Federal Medical and Biological Agency at 30-34 weeks' gestation period (group of smokers - 80 people and non-smokers - 40 people); 85.0% of pregnant smokers have a slight degree of nicotine dependence, 5.0% - a moderate, and 10.0% - strong according to Fagerstrem's test; smoking history was 10,6 ± 3,9 years. Changes in the feto-placental blood flow predominate in the group of the pregnant smoking women. It is indicated by the systolic-diastolic ratio and resistance index, reflecting the kind of "brain protection effect of the fetus" and occurred in Doppler signs of increased blood flow in the middle cerebral fetal artery, against decrease of blood flow in the umbilical artery. The necessity is justified to spend additional Doppler study of utero-placental, feto-placental and fetal blood flow to identify compensatory changes in placenta blood vessels, umbilical cord and forecasting the development of hypoxia in the fetus of vascular origin, during the third ultrasound screening of smoking pregnant women.

According to the classical and modern concepts the organization of functional hemispheric asymmetry is an interesting issue for different specialists. This article reviews current data on fixed and dynamic properties of the cerebral hemispheres functional specialization. The article covers the issues of functional insufficiency of hemispheric interrelations associated with some diseases, gives comparative analysis of parameters of social and psychological adaptation of individuals with one-hemisphere dominance, and presents features of lateralization of brain function in healthy males and females and those with pathology. The authors emphasize the leading role of the corpus collosum in hemispheric interrelations, reveal the features of hemispheric asymmetry of right-handed and left-handed individuals based on interaction of the cortex and the brain regulatory systems during quiet wake, dynamism and falling asleep. The article also focuses on the features of brain function lateralization of some athletes and hemispheric interrelations in different phases of desynchronosis and during organism ageing in normal and stressful ecological conditions. The authors address the issue of the relationship of pregnancy and the brain lateralization, as well as the functional specialization of the cerebral hemispheres with the asymmetry of the autonomic nervous system.

The purpose of the work is a comparative characteristic of indicators efficiency of relative epidemiological risk of primary and general incidence in estimating medico-ecological situation and mass non-communicable diseases of the population. To achieve the goals and tasks a retrospective study of the child's incidence in the years 2000-2012 was carried out in the 33 administrative territories of the Irkutsk region based on the statistical reporting (Form №12). The relative risk of primary and general morbidity of all diseases and of 11 separate classes was calculated using regional background incidence rates obtained by the statistics. The intensity degree of medico-ecological situation on the territory was determined by the varied criteria on the basis of sigma - deviations, waviness and tendencies of dynamics development of incidence relative risks in time were revealed by a smoothed method of sliding simple average values for 3 years and according to polynomial approximation of the 5th order. The research was carried out in 5 cities with the developed industry and 5 nonindustrial areas. The analysis of the average, increased and high risk rates of the general and primary diseases incidence of separate classes in children during the considered period on the territory of the industrial cities and nonindustrial areas has shown that we gain a better understanding about a degree of medico-ecological situation intensity in the studied territories when sharing risk indicators of the general and primary incidence. Undulating risk dynamics of general and primary morbidity in the period under review differ depending on the area, the class of illnesses and morbidity. This reflects the particular cyclical fluctuations of states with respect to low and high resistance to the pathogenic factor effects. Joint use of the risk indicators of primary and general child's morbidity is necessary to carry out while analyzing data of social and hygiene monitoring to assess the intensity degree of medical and ecological situation and mass (with higher and high risk levels) non-communicable morbidity.