Vol 20, No 3 (2013)

A clinico-epidemiological and laboratory study of 167 patients with different forms of rotavirus infection at the age from 3 months to 17 years was carried out in the period of 2008-201 1. The children with the moderate form of the disease (56.29 %) and the children aged 1-3 years - 74 (44.32 %) - dominated. The children were hospitalized more frequently during the spring months (39.52 %) and in the winter months (29.34 %). The symptoms of the rotavirus infection in children of all ages had peculiarities depending on the forms of the disease; the intoxication, gastroenterological, catarrhal syndromes dominated.

Special surfaces based on titanium dioxide are developed for prevention of nosocomial infections. The reactive oxygen species (ROS) have been generated by the surfaces after their UV-irradiation. ROS caused destruction of bacteria. However, effectiveness of bactericidal activity of ТiO 2-films depends on several factors. Influence of time of UV irradiation, thermal (annealing) and chemical (benzene) treatment of films on the bactericidal activity, as well as the bactericidal effect against suspended and lyophilized bacteria have been studied. Three clinical isolates Staphylococcus aureus 956, Staphylococcus epidermidis 1061, Escherichia coli 321-5 have been used. Viability of the suspended bacteria has been determined with use of the classical method of counting CFU, viability of lyophilized bacteria has been determined with use of the method of estimation of coefficients of bactericidal extinction of control and test samples. It has been shown that the bactericidal effect of thin films against all strains increased with an increase in the flow of UV exposure. dermal and chemical treatment caused bactericidal activity recovery which was lost during the initial incubation of the bacterial suspension on the surface. Absence of fluid in the system increased the bactericidal activity of TiO 2-films.

The dynamics of suicide mortality in adolescence and its relationship with the level of alcohol consumption in the Murmansk region have been analyzed. The method of autoregression and integrated moving average (ARIMA) was used. The alcohol attributiveness of the male population mortality has been revealed.

Sepsis developing in early periods of the burn disease is characterized by extremely severe and lightning-like course, diagnostic complexity, increased lethality. The hemostasis system state and biochemical blood metabolites were studied in 100 patients with severe burns, among them, the burn disease was complicated by sepsis in 33 patients, it wasn’t observed in 67 patients. It has been clearly shown that “early” sepsis development in the seriously burned patients occurred against unbalance of the hemostasis system: an increased coagulation potential and a sharp decrease of blood anticoagulation mechanisms. Hemastasiological disorders were accompanied by the kidneys and liver increased functional deficiency. The hemostasis system indexes can be included into complex examinations of patients aimed at prognosis of development, identification and estimation of severity of “early” sepsis in seriously burned patients.

Агаджанян Н. А., Радыш И. В. Биоритмы, среда обитания, здоровье. -М. : РУДН, 2013. - 362 с.