Vol 24, No 5 (2017)

The authors have carried out a review of traffic accidents occurrence the Republic of Kazakhstan in 2013-2015. A favorable trend -indices decrease of traffic accidents from 2013 has been revealed as well as considerable differences between the regions of Kazakhstan according to the figures have been discovered. Country regions with the most unfavorable situation in traffic accidents and population mortality as a result of traffic accidents have been specified. Among them: Almaty region, Kyzylorda region, Atyrau region, Karaganda region and Mangistau region. The necessity to set a trauma registry has been specified. It allows to work out programs of traffic accidents primary prevention considering regions' local peculiarities.

The behavior dynamics of entropy E value in one man with multi repetition of tremor registration (N = 225 repetition) has been studied according to Eskov-Zinchenko theory effect in biomechanics. Almost full E coincidence according to 15-th series consisting of 15 tremorograms each proves the stable value of E for all 225 such registration (with repetition). It is like deterministic chaos. But the stress effect (2 min cooling of limb in water with t 4 °C does not show significant change of E value in tremorograms of three groups of test persons comparing with their initial state. There is a necessity to use another criteria for cold stress assessment (not stochastic approach) while creating special condition for cool adaptation (cold water treatment during 1 year and 2 years). Entropy E as a chaos measure is ineffective for assessment such adaptation procedures for the human body in the North. At the same time, matrix computation of paired comparison of tremorograms selection shows the lack of statistical stability in these samples, i. e., for two received samples, we are unable to obtain two identical statistical distribution functions. This effect was called Eskov-Zinchenko effect and now we prove that the values of entropy E of the obtained samples remain unchanged. Entropy stationarity for different states of homeostasis is one more proof of the systems' features of the third type in human ecology.

The article deals with the important problem in pediatrics - assessment of vitamin D status by level of metabolite 25 (OH) D (calcidiol) in the peripheral blood of adolescents with hypertension. The study included 87 children aged 12-17 years with various degree of essential arterial hypertension severity. Insufficiency of vitamin D was observed in 84 % (17.0 ± 4.89) ng/ml, deficiency of vitamin D was observed in 11,5 % (8.03 ± 1.24) ng/ml). The degree of vitamin D insufficiency in children with hypertension and metabolic syndrome is higher than in children with hypertension and without metabolic syndrome. Vitamin D content also depends on the age, the younger adolescent the higher insufficiency of vitamin D. Among 14th years old children its level was (14.7 ± 4.46) ng/mL, among 17th years old adolescents it was (18.1 ± 6.23) ng/ml. The lowest level of 25(OH)D was found in February (11.3 ± 4.08) ng/ml. The highest content of active vitamin D metabolite found in July - (27.6 ± 5.56) ng/ml.

The proportion of the craniocerebral injuries (CI) is 25-40 % of all kinds of injuries in the world. The mortality rate due to ChMT is 30 persons per 100 thousand of the population, and over a third of victims die in medical institutions in the first three days after entering. The research of immune system condition and its role in formation of clinical implications, possible complications in victims with ChMT remains a poorly studied problem. Few literary data reflect results of surgical interventions in a brain or fighting (explosive) injuries for 3-5 days. Reactions of adaptive immunity and compensatory immune reactions in the first days after a trauma represent a class of the protective and adaptive phenomena which develop only in extreme conditions, show response to damage and can be reactions of cascade type and can compensate a neurologic injury. The complex immunologic research of victims in the first days after a trauma will allow to determine parameters which will help to prognosticate character of possible complications, to lower disability percent. The increased values of immunologic indicators are marked in 25,0-66,7 % of persons with moderate trauma severity (CD10+, CD16+, IL-2, CD8+, IgE, IL-6) and in 16,7-100 % of victims with serious degree of ChMT (CD8+, CD16+, CD71+, CD95+, CD25+, IL-6, -10, IgE, IgM, HLA-DR+), at the same time a wider range of indicators involve in the adaptive immune response. In the first days after getting injured rising of values of cytokine and cytotoxic activity testifies to the expressed tension in the immune system that promotes reduction of spare capacities of immune homeostasis in victims and development of secondary ecologically dependent immune imbalances in the form of complications.