No 5 (2017)

Articles
PREDICTIVE ASSESSMENT OF INDIVIDUAL HUMAN SUSCEPTIBILITY TO DAMAGING COLD EXPOSURE
Chashchin V.P., Gudkov A.B., Chashchin M.V., Popova O.N.
Abstract
According to a systematic review of published data in both the national and international scientific indexing systems, including the results of our own researches, there have been selected evidence-based criteria and internal genotype-phenotype risk determinants for assessing the individual susceptibility to the acute cold exposure. In accordance with these criteria, the list of cold-related health conditions was defined. This list includes 33 classes and groups of diseases and conditions by ICD-10 codes, arising from or tightly associated with the cold exposure. According to the comorbidity principles, the novel quantitative predictive model for assessing the individual susceptibility to the acute cold exposure was developed and validated. This assessment takes into account, in addition to the meteorological risk factors, also internal risk determinants, including physical status, behavioral, pathogenic and functional disorders, as well as receiving thermoregulation-altering pharmaceuticals prescribed by recommended therapeutic doses. The algorithm for calculating the individual health risk and recommended time limits based on the use of suggested comorbidity index for the acute exposure to cold in an open area or in unheated premises without special active thermal protection is described.
Ekologiya cheloveka (Human Ecology). 2017;(5):3-13
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EPIDEMIOLOGY OF TRAFFIC ACCIDENTS IN KAZAKHSTAN IN 2013-2015
Abdrakhmanova Z.B., Buleshov M.A., Moldaliyev I.S., Buleshova A.M., Ivanov S.V., Grjibovski A.M.
Abstract
The authors have carried out a review of traffic accidents occurrence the Republic of Kazakhstan in 2013-2015. A favorable trend -indices decrease of traffic accidents from 2013 has been revealed as well as considerable differences between the regions of Kazakhstan according to the figures have been discovered. Country regions with the most unfavorable situation in traffic accidents and population mortality as a result of traffic accidents have been specified. Among them: Almaty region, Kyzylorda region, Atyrau region, Karaganda region and Mangistau region. The necessity to set a trauma registry has been specified. It allows to work out programs of traffic accidents primary prevention considering regions' local peculiarities.
Ekologiya cheloveka (Human Ecology). 2017;(5):14-20
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INFORMATIONAL AND COMMUNICATIVE BASIS OF THE ENVIRONMENTAL SAFETY IN THE ARCTIC
Vilova T.V., Chertova N.A., Vilova M.G., Permilovskiy M.S.
Abstract
The paper deals with the conditions of efficiency of states' information cooperation, the importance of ecological communication while providing environmental safety as well as peculiarities of legal regulation of information support of environmental safety in the Arctic. The authors analyzed the concept of environmental communication and suggested the idea of a communicative legitimacy creation, intending the process of gathering, accumulation and dissemination of information about the environment state in the Arctic should be carried out with the aim of ensuring environmental safety. The actual problems of creation of a uniform information space in the Arctic have been studied in the paper. It is stated that the national Arctic policy is being developed in the Russian Federation. This policy should be based on principles of openness, cooperation and awareness of the results of the Arctic zone development. In this study the authors came to the conclusion that the creation of organizational and legal mechanisms of interaction between the Arctic countries will contribute to the environmental safety in the Arctic zone. The authors established a relationship between the creation of current exchange of ecological information systems and environmental security in the Arctic in the interests of sustainable development.
Ekologiya cheloveka (Human Ecology). 2017;(5):21-26
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GLANSDORFF-PRIGOGINE THEOREM IN THE DESCRIPTION OF TREMOR CHAOTIC DYNAMICS IN COLD STRESS
Eskov V.M., Zinchenko Y.P., Filatov M.A., Ilyashenko L.K.
Abstract
The behavior dynamics of entropy E value in one man with multi repetition of tremor registration (N = 225 repetition) has been studied according to Eskov-Zinchenko theory effect in biomechanics. Almost full E coincidence according to 15-th series consisting of 15 tremorograms each proves the stable value of E for all 225 such registration (with repetition). It is like deterministic chaos. But the stress effect (2 min cooling of limb in water with t 4 °C does not show significant change of E value in tremorograms of three groups of test persons comparing with their initial state. There is a necessity to use another criteria for cold stress assessment (not stochastic approach) while creating special condition for cool adaptation (cold water treatment during 1 year and 2 years). Entropy E as a chaos measure is ineffective for assessment such adaptation procedures for the human body in the North. At the same time, matrix computation of paired comparison of tremorograms selection shows the lack of statistical stability in these samples, i. e., for two received samples, we are unable to obtain two identical statistical distribution functions. This effect was called Eskov-Zinchenko effect and now we prove that the values of entropy E of the obtained samples remain unchanged. Entropy stationarity for different states of homeostasis is one more proof of the systems' features of the third type in human ecology.
Ekologiya cheloveka (Human Ecology). 2017;(5):27-32
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WAVELET ANALYSIS OF CLIMATE FACTORS VARIATIONS OF KHANTY-MANSIYSK CITY
Ragozin O.N., Korchin V.I., Shalamova E.Y., Ragozina E.R.
Abstract
The aim of this study is to identify the complex temporary cycles in fluctuations of climatic factors in Khanty-Mansiysk using wavelet analysis. The dynamics of temperature fluctuations in the period 2001 and 2014 shows a significant circannual cycle. Variations of barometric pressure are polycyclic. Descending capacity of rhythms with a period of 5.57 years; 1.02 years and rhythms close to the semiannual, seasonal and cirradian: 173.4 days; 109.3 days; 37.2 days are observed. Humidity varies in circumannual rhythm, intraannual dynamic is the following: 173.4 days; 127.5 days; 68.9 days. Barometric tendency except circannual rhythm is characterized by the rhythm with a period of 3.01 years, and intra-annual intercalary: 173.4 days; 109.3 days; 59.1 days and 20.1 days. Changes of wind speed do not have circannual rhythm, but there are intra-annual variations with a period of 81.1 days and 40.2 days. The oxygen volume being calculated maintains the basic rhythm of such components as temperature, barometric pressure and humidity, namely circannual: two years, five years; two- one month. Indicators of air temperature, wind speed and barometric tendency show the greatest amplitude of oscillation. Visual analysis of coherence of individual rhythms with the same period reveals a florid desynchronosis, which explains negative correlation between the climatic parameters. Use of wavelet analysis to assess the short-term component of the climate processes allows to reveal periodical and aperiodical intercalary rhythms. These rhythms interfering with the steady beat identified by Fourier transform allow us to explain unsteady rhythmic changes implemented in climatic time series.
Ekologiya cheloveka (Human Ecology). 2017;(5):33-37
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ASSESSMENT STATUS OF VITAMIN D IN ADOLESCENTS WITH ESSENTIAL HYPERTENSION
Zeid S.K., Yakovleva L.V.
Abstract
The article deals with the important problem in pediatrics - assessment of vitamin D status by level of metabolite 25 (OH) D (calcidiol) in the peripheral blood of adolescents with hypertension. The study included 87 children aged 12-17 years with various degree of essential arterial hypertension severity. Insufficiency of vitamin D was observed in 84 % (17.0 ± 4.89) ng/ml, deficiency of vitamin D was observed in 11,5 % (8.03 ± 1.24) ng/ml). The degree of vitamin D insufficiency in children with hypertension and metabolic syndrome is higher than in children with hypertension and without metabolic syndrome. Vitamin D content also depends on the age, the younger adolescent the higher insufficiency of vitamin D. Among 14th years old children its level was (14.7 ± 4.46) ng/mL, among 17th years old adolescents it was (18.1 ± 6.23) ng/ml. The lowest level of 25(OH)D was found in February (11.3 ± 4.08) ng/ml. The highest content of active vitamin D metabolite found in July - (27.6 ± 5.56) ng/ml.
Ekologiya cheloveka (Human Ecology). 2017;(5):38-41
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ANTIBODIES, SPECIFIC TO BENZO[A]PYRENE AND ESTRADIOL, IN HEALTHY MEN AND LUNG CANCER PATIENTS
Glushkov A.N., Polenok E.G., Kostyanko M.V., Titov V.A., Vafin I.A., Ragozhina S.E.
Abstract
It is known that the polycyclic aromatic hydrocarbons, particularly benzo[a]pyrene (Bp), are the most common initiators of carcinogenesis, and estradiol (Es) is the most studied endogenous promoter. However, specific immune responses to exogenous and endogenous carcinogenic factors are still insufficiently studied. This paper presents the results of research of antibodies class A and G (IgA and IgG), specific to Bp and Es, in serum of 272 healthy men and 380 patients with non-small cell lung cancer (NSCLC) using a semi-quantitative immunoassay. The purpose of research - to identify the features of antibodies to Bp and Es in NSCLC patients according to the possible individual combinations of their levels in serum. The separated increasing of IgA and IgG antibodies to BP or to Es were found in NSCLC patients more often then in healthy donors (OR = 1,6-1,8). These differences were more significant at the simultaneous increasing of IgA and IgG antibodies to Bp and Es. Probably, induction of specific immunity against exogenous chemical carcinogens and endogenous steroids take part in initiation and promotion of carcinogenesis in human. The method used in this study is recommended for inclusion to the laboratory complex for cancer risk detection, first of all, in the workers of carcinogenic hazardous enterprises.
Ekologiya cheloveka (Human Ecology). 2017;(5):42-46
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IMMUNOLOGIC REACTIVITY IN THE FIRST DAYS AFTER THE CRANIOCEREBRAL TRAUMA
Shchegoleva L.S., Popovskaya E.V., Shashkova E.Y., Sidorovskaya O.E., Balashova S.N.
Abstract
The proportion of the craniocerebral injuries (CI) is 25-40 % of all kinds of injuries in the world. The mortality rate due to ChMT is 30 persons per 100 thousand of the population, and over a third of victims die in medical institutions in the first three days after entering. The research of immune system condition and its role in formation of clinical implications, possible complications in victims with ChMT remains a poorly studied problem. Few literary data reflect results of surgical interventions in a brain or fighting (explosive) injuries for 3-5 days. Reactions of adaptive immunity and compensatory immune reactions in the first days after a trauma represent a class of the protective and adaptive phenomena which develop only in extreme conditions, show response to damage and can be reactions of cascade type and can compensate a neurologic injury. The complex immunologic research of victims in the first days after a trauma will allow to determine parameters which will help to prognosticate character of possible complications, to lower disability percent. The increased values of immunologic indicators are marked in 25,0-66,7 % of persons with moderate trauma severity (CD10+, CD16+, IL-2, CD8+, IgE, IL-6) and in 16,7-100 % of victims with serious degree of ChMT (CD8+, CD16+, CD71+, CD95+, CD25+, IL-6, -10, IgE, IgM, HLA-DR+), at the same time a wider range of indicators involve in the adaptive immune response. In the first days after getting injured rising of values of cytokine and cytotoxic activity testifies to the expressed tension in the immune system that promotes reduction of spare capacities of immune homeostasis in victims and development of secondary ecologically dependent immune imbalances in the form of complications.
Ekologiya cheloveka (Human Ecology). 2017;(5):47-53
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THE POPULATION-BASED CANCER REGISTRY AS A RESOURCE FOR RESEARCH AND PRACTICAL HEALTHCARE
Valkov M.Y., Karpunov A.A., Coleman M.P., Allemani C., Pankratieva A.Y., Potekhina E.F., Valkova L.E., Grjibovski A.M.
Abstract
Population-based cancer registries collect a standardized dataset about all patients diagnosed with a malignancy who live in the defined territory covered by the registry, from initial diagnosis through investigation and treatment, to the eventual death of the patient. This enables estimation of the cancer burden and surveillance of trends over time, as the evidence base for cancer control policies. There are more than 300 population-based cancer registries around the world, covering about 5% of the world's population, but the proportion is much higher in developed countries than in developing countries. Adherence to international standards of data collection and quality control is extremely important, because it enables robust comparisons of incidence, prevalence and survival, both between the regions of the country and internationally. These comparisons inspire changes in cancer prevention, and clinical practice, and progress in the organisation and delivery of policies for cancer control. The examples of such comparisons are international projects Cancer Incidence in Five Continents, Globocan and the CONCORD programme for the global surveillance of cancer survival. In this article, we describe the organisation and experience of practical application of data from the Arkhangelsk regional cancer registry, both within Russia and in international collaborations.
Ekologiya cheloveka (Human Ecology). 2017;(5):54-62
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Retsenziya na monografiyu «Osobennosti sovremennogo travmatizma: patogeneticheskie, lechebnye i organizatsionnye aspekty»
Akhtyamov I.F.
Abstract
Ekologiya cheloveka (Human Ecology). 2017;(5):63-64
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